- RESPIRATORY TRACT DRUGS
- Pharmaceutical Form : Capsules
- Composition : Ambroxol HCl 75 mg / Cap
- Active Substance : Ambroxol HCl
Preclinically , Ambroxol , the active ingredient of Ambroxol – Medico , has been shown to
increase respiratory tract secretion. It enhances pulmonary surfactant production and stimulates ciliary activity . These actions result in improved mucus flow and transport ( mucociliary clearance ).
Improvement of mucociliary clearance has been shown in clinical pharmacological studies . Enhancement of fluid secretion and mucociliary clearance facilitates expectoration and eases cough .
Secretolytic therapy in acute and chronic bronchopulmonary diseases associated with abnormal mucus secretion and impaired mucus transport .
Ambroxol – Medico should not be used in patients known to be hypersensitive to Ambroxol or other components of the formulation .
Side Effects : Ambroxol – Medico is generally well tolerated . Mild upper gastro-intestinal side effects
(primarily pyrosis , dyspepsia, and occasionally nausea, vomiting) have been reported, principally following parenteral administration.
Allergic reactions have occurred rarely, primarily skin rashes.There have been extremely rare case reports of severe acute anaphylactic-type reactions but their relationship to Ambroxol – Medico is uncertain. Some of these patients have also shown allergic reactions to other substances .
Pregnancy and Lactation:
It is prefer not to use this product during pregnancy and lactation .
Interactions : Administration of Ambroxol – Medico together with antibiotics ( Amoxicilline, Cefuroxime, Erythromycine, Doxycycline ) leads to higher antibiotic concentration in the lung tissue .
No clinically relevant unfavourable interaction with other medications have been reported.
Dosage and Administration
Tablets 30 mg
Adults : 1 tablet 3 times daily
The therapeutic effect may be enhanced by administering 2 tablets 2 times daily .
The tablets should be taken after meals with liquid
Capsules 75 mg SR
Adults : 1 capsule once daily , in the morning or evening after a meal .
The capsule should not be opened or chewed, but swallowed whole with ample liquid .
Adults and children over 12 years :
5 ml – 10 ml ( 1 – 2 tsps. ) 3 times daily
For the therapy of acute respiratory tract disorders and for the initial treatment of chronic conditions up to 14 days, the dose may be increased to 20 ml(2 tablespoons ) 2 times daily .
For the treatment of children under the age of 12 the following dosage regimen is recommended depending on the severity of the disease :
Syrup 15 mg/ 5 ml = 1 teaspoonful
Children 6 – 12 years : 5 ml ( 1 tsp.) 2 – 3 times daily
Children 2 – 6 years : 2.5 ml (½ tsp. ) 3 times daily
Children under 2 years : 2.5 ml ( ½ tsp. ) 2 times daily
Ambroxol Medico Syrup should be taken at mealtimes .
Storage Conditions : Store in a dry pleace below 25oC
Ambroxol – Medico ( Tablets ) :20 Tablet in a box .
Ambroxol – Medico 75 ( Capsules ) : (10 – 20) Capsule in a box .
Ambroxol – Medico ( Syrup ) : Bottle of 100 ml